179 Prevalence of silent myocardial infarction in patients with left ventricular systolic dysfunction and associations with dysglycaemia

Introduction Cardiovascular magnetic resonance (CMR) is recommended in both NICE and ESC guidelines patients with new onset left ventricular systolic dysfunction (LVSD) to identify aetiology. In LVSD, type 2 diabetes associated increased prevalence of silent myocardial infarction (MI). We aimed investigate if MI LVSD are larger diabetic compared non-diabetic patients. Methods Clinical CMR data from 156 who underwent cardiac MRI determine the aetiology were found have evidence a analysed. Patients identified two ongoing studies (National Research Ethics Committee numbers 17/YH/0300 21/PR/0318) Exclusion criteria any history chest pain, prior infarction, previous revascularisation. categorised into normoglycaemia, pre-diabetic groups according diagnosis HbA1c (diabetes >47mmol/mol, prediabetes 42-47mmol/mol). Size was quantified by scoring number affected segments American Heart Association 16-segement model. Results Overall, there individuals, 124 (79.4%) these being male mean age 66.6 years ± 10.45. Of our cohort 47 (30%) defined as diabetic, 31 (20%) 78 (50%) normoglycaemic. Inferior infero-lateral infarcts most this consistent between non, pre patients, segment 5 (basal inferolateral) non-diabetics diabetics (42.3% 46.8% diabetics), 15 (apical inferior) pre-diabetics (48.5%). normoglycaemic infarcted 3.91±2.84, 4.84±3.31 4.09±2.63 diabetics. Discussion Our did not reveal an association infarct size status population had infarct. inferolateral infarcts, however, also status. Conflict Interest Nil